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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC42
All Species:
21.82
Human Site:
T222
Identified Species:
53.33
UniProt:
Q9Y546
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y546
NP_443172.1
428
48571
T222
D
A
G
V
R
K
M
T
A
P
V
R
V
M
K
Chimpanzee
Pan troglodytes
XP_513419
427
48389
T222
D
A
G
V
R
K
M
T
A
P
V
R
V
M
K
Rhesus Macaque
Macaca mulatta
XP_001113087
428
48535
T222
D
A
G
V
R
K
M
T
A
P
V
R
V
M
K
Dog
Lupus familis
XP_865934
428
48365
T222
D
A
G
V
R
K
M
T
A
P
V
R
V
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2U7
421
47930
R219
C
L
S
D
A
G
I
R
K
M
T
A
P
V
R
Rat
Rattus norvegicus
Q4KM95
421
47895
R219
C
L
S
D
A
G
I
R
K
M
T
A
P
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505744
531
57903
T326
D
A
G
I
R
K
M
T
A
P
V
R
V
M
R
Chicken
Gallus gallus
XP_422489
421
47625
L218
N
A
L
S
D
A
G
L
R
R
M
T
A
P
V
Frog
Xenopus laevis
Q4KLV2
417
47094
T215
N
I
G
I
Q
K
M
T
A
S
V
R
V
L
G
Zebra Danio
Brachydanio rerio
Q6P5J6
407
46385
D204
M
G
A
N
C
L
S
D
A
G
L
Q
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.5
94.3
N.A.
87.1
88
N.A.
49.3
71
50.7
46.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
99.3
97.4
N.A.
92.2
92.9
N.A.
60.2
81.5
69.3
65.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
86.6
6.6
53.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
100
20
80
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
10
0
20
10
0
0
70
0
0
20
10
0
0
% A
% Cys:
20
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
20
10
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
60
0
0
20
10
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
20
0
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
60
0
0
20
0
0
0
0
0
40
% K
% Leu:
0
20
10
0
0
10
0
10
0
0
10
0
0
20
0
% L
% Met:
10
0
0
0
0
0
60
0
0
20
10
0
0
50
0
% M
% Asn:
20
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
50
0
0
20
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
50
0
0
20
10
10
0
60
10
0
30
% R
% Ser:
0
0
20
10
0
0
10
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
60
0
0
20
10
0
0
10
% T
% Val:
0
0
0
40
0
0
0
0
0
0
60
0
60
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _